Abnova™ Human PRKCZ (Z15108, 6 a.a. - 584 a.a.) Partial Recombinant Protein with GST-His tag expressed in Sf9 cells

Used for Func, SDS-PAGE

Manufacturer:  Abnova™ P4764

Catalog No. 89-958-200

Description

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

• Accession Number: Z15108
• Concentration: 0.181 ug/uL
• Format: Liquid
• Gene ID (Entrez): 5590
• Name: PRKCZ (Human) Recombinant Protein
• Purification Method: One-step affinity purification using GSH agarose
• Quantity: 100 ug
• Regulatory Status: RUO
• Common Name: PRKCZ
• Biological Activity: 83pmol/μg x min
• Recombinant: Yes

• Expression System: Insect cell (Sf9) expression system
• For Use With (Application): Functional Study, Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis
• Formulation: Liquid
• Molecular Weight: 96.654kDa
• Preparation Method: Insect cell (Sf9) expression system
• Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing
• Gene Alias: PKC-ZETA|PKC2
• Gene Symbol: PRKCZ
• Host Species: Insect
• Protein Tag: GST-His