Invitrogen CD23 (Soluble) Human ELISA Kit
For the quantitative detection of human sCD23.
Manufacturer: Invitrogen BMS2272
DescriptionCD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
|Plasma, 100 μL|Serum, 100 μL|Supernatant, 100 μL|
|1 hr. 20 min.|
|Immunoglobulin E receptor low affinity II|
|Adhesive Plate Covers|
|2°C to 8°C|
|3 hr. 10 min.|
|Plasma, Serum, Supernatant|
|Colorimetric Microplate Reader|
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For Research Use Only