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Gibco™ Human TIGAR-TAT Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Supplier:  Gibco™ 15014T100UG

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Catalog No. 15014T100UG


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Description

Description

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other intracellular proteins into primary, as well as transformed, cells.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Q9NQ88
protein with no preservative
31.6
100 μg
-20°C
<1 EU/μg
TIGAR
Unconjugated
ARFALTVVRH GETRFNKEKI IQGQGVDEPL SETGFKQAAA AGIFLNNVKF THAFSSDLMR TKQTMHGILE RSKFCKDMTV KYDSRLRERK YGVVEGKALS ELRAMAKAAR EECPVFTPPG GETLDQVKMR GIDFFEFLCQ LILKEADQKE QFSQGSPSNC LETSLAEIFP LGKNHSSKVN SDSGIPGLAA SVLVVSHGAY MRSLFDYFLT DLKCSLPATL SRSELMSVTP NTGMSLFIIN FEEGREVKPT VQCICMNLQD HLNGLTETRG GGYGRKKRRQ RRR
≥ 95% by SDS-PAGE gel and HPLC analyses.
Functional Assay
57103
Human TIGAR-TAT
E. coli
RUO
TIGAR
Human
Recombinant
Lyophilized
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