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Gibco™ Human TIGAR-TAT Recombinant Protein, PeproTech®
E. coli Recombinant Protein
Supplier: Gibco™ 15014T1MG
This item is not returnable.
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Description
TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other intracellular proteins into primary, as well as transformed, cells.Specifications
Q9NQ88 | |
protein with no preservative | |
31.6 | |
1 mg | |
-20°C | |
<1 EU/μg | |
TIGAR | |
Unconjugated | |
ARFALTVVRH GETRFNKEKI IQGQGVDEPL SETGFKQAAA AGIFLNNVKF THAFSSDLMR TKQTMHGILE RSKFCKDMTV KYDSRLRERK YGVVEGKALS ELRAMAKAAR EECPVFTPPG GETLDQVKMR GIDFFEFLCQ LILKEADQKE QFSQGSPSNC LETSLAEIFP LGKNHSSKVN SDSGIPGLAA SVLVVSHGAY MRSLFDYFLT DLKCSLPATL SRSELMSVTP NTGMSLFIIN FEEGREVKPT VQCICMNLQD HLNGLTETRG GGYGRKKRRQ RRR | |
≥ 95% by SDS-PAGE gel and HPLC analyses. |
Functional Assay | |
57103 | |
Human TIGAR-TAT | |
E. coli | |
RUO | |
TIGAR | |
Human | |
Recombinant | |
Lyophilized |
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