Gibco™ Human TIGAR-TAT Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Catalog Number	Mfr. No.	Quantity
15014T100UG	Gibco™ 15014T100UG	100 μg
150-14T-1MG	Gibco™ 15014T1MG	1 mg
15014T250UG	Gibco™ 15014T250UG	250 μg
15014T25UG	Gibco™ 15014T25UG	25 μg
15014T500UG	Gibco™ 15014T500UG	500 μg
150-14T-5UG	Gibco™ 15014T5UG	5 μg

Description

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other intracellular proteins into primary, as well as transformed, cells.

Specifications

• Accession Number: Q9NQ88
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 31.6
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: TIGAR
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized

• For Use With (Application): Functional Assay
• Gene ID (Entrez): 57103
• Name: Human TIGAR-TAT
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: TIGAR
• Conjugate: Unconjugated
• Sequence: ARFALTVVRH GETRFNKEKI IQGQGVDEPL SETGFKQAAA AGIFLNNVKF THAFSSDLMR TKQTMHGILE RSKFCKDMTV KYDSRLRERK YGVVEGKALS ELRAMAKAAR EECPVFTPPG GETLDQVKMR GIDFFEFLCQ LILKEADQKE QFSQGSPSNC LETSLAEIFP LGKNHSSKVN SDSGIPGLAA SVLVVSHGAY MRSLFDYFLT DLKCSLPATL SRSELMSVTP NTGMSLFIIN FEEGREVKPT VQCICMNLQD HLNGLTETRG GGYGRKKRRQ RRR
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.