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R&D Systems™ Recombinant Human TSHR Fc Chimera Protein, CF

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Manufacturer:  R&D Systems™ 8950TR050

Catalog No. 89-50T-R050

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The Recombinant Human TSH R Fc Chimera Protein is derived from CHO. The Recombinant Human TSH R Fc Chimera Protein has been validated for the following applications: Bioactivity.


Chinese Hamster Ovary cell line, CHO-derived Human TSH R (Met22-Gly413) Accession # P16473, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
CHNG1, LGR3, LGR3hTSHR-I, MGC75129, seven transmembrane helix receptor, thyroid stimulating hormone receptor, Thyroid-stimulating hormone receptor, thyrotropin receptor, thyrotropin receptor-I, hTSHR-I, TSH R, TSH-R
Theoretical M.W.: 71kDa
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
Chinese Hamster Ovary cell line,CHO-derived human TSH R protein, (N-terminus) Human TSH R (Met22-Gly413) Accession &Num; P16473 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
<0.10 EU per 1μg of the protein by the LAL method.
Measured by its ability to inhibit rhTSH-induced cAMP accumulation in HEK293 human embryonic kidney cells transfected with human TSH R. The ED50 for this effect is typically 2-12μg/mL.
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