Tocris™ Hydroxy Dynasore

Dynamin inhibitor; analog of dynasore (Cat. No. 2897)

Manufacturer: Tocris™ 5364/50

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Catalog No. 53-645-0

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For Research Use Only


    Description Hydroxy Dynasore
    Quantity 50mg
    Product Type Hydroxy Dynasore
    Molecular Weight 338.31
    Purity >98

    Dynamin inhibitor (IC50 values are 0.38 and 2.6µM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons. Also protects against botulinum A-induced muscle paralysis in rats. Analog of Dynasore (Cat. No. 2897).

    • Chemical Name: 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
    • Formula: C18H14N2O5
    • CAS Number: 1256493-34-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

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