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  7. Hydroxychloroquine sulfate, 98%, Thermo Scientific Chemicals

Hydroxychloroquine sulfate, 98%, Thermo Scientific Chemicals

Catalog Number ac263010250
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Quantity:
25 g
100 g
Packaging:
Glass bottle
747-36-4
C18H26ClN3O·H2SO4
433.96
MFCD00078203
JCBIVZZPXRZKTI-UHFFFAOYSA-N
hydroxychloroquine sulfate, hydroxychloroquine sulphate, ercoquin, plaquinol, toremonil, 2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate, hydroxychloroquine sulfate usp, plaquenil tn, hydroxychloroquine; sulfuric acid, dsstox_cid_27788
12947
2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid
CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O
747-36-4
C18H26ClN3O·H2SO4
433.96
MFCD00078203
JCBIVZZPXRZKTI-UHFFFAOYSA-N
hydroxychloroquine sulfate, hydroxychloroquine sulphate, ercoquin, plaquinol, toremonil, 2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate, hydroxychloroquine sulfate usp, plaquenil tn, hydroxychloroquine; sulfuric acid, dsstox_cid_27788
12947
2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid
CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

Description

Hydroxychloroquine sulfate, CAS # 747-36-4, is a chemical compound with antiparasitic, antiviral, and anti-rheumatic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Hydroxychloroquine sulfate shows antimalarial activity against malaria parasites mainly in the intra-erythrocytic phase of its life cycle. It acts by inhibiting the heme polymerase inside the food vacuole of the parasites
  • It shows an inhibitory activity in autophagy preventing the lysosome fusion with the autophagosome
  • Some studies demonstrated that hydroxychloroquine sulfate, due to its antiviral activity can restrict HIV infection in vitro

Applications

  • Hydroxychloroquine sulfate displays antiviral and anti-rheumatic activities
  • In vitro and in vivo experiments have been performed to investigate the role of hydroxychloroquine sulfate in the treatment of SARS-CoV-2 disease
  • Hydroxychloroquine sulfate can be used in immunofluorescence assays to evaluate the antiviral mechanisms in dengue virus-2 infection. In this disease, this compound can activate the innate immune response
TRUSTED_SUSTAINABILITY
Melting Point 240.0°C
Color White
Loss on Drying 2% max. (105°C, 2 hrs.)
Infrared Spectrum Authentic
Assay Percent Range 0.98
Packaging Glass bottle
Quantity 25 g
Merck Index 15, 4857
Solubility Information Solubility in water: soluble. Other solubilities: practically insoluble in alcohol,chloroform,,ether,acetone and acetic acid
Formula Weight 433.96
Percent Purity 98%
Physical Form Crystalline Powder
Chemical Name or Material Hydroxychloroquine sulfate
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Safety and Handling

Hazard Category Serious eye damage/eye irritation (category 2), Acute toxicity (category 4)
Hazard Statement Causes serious eye irritation, Harmful if swallowed
EINECSNumber 212-019-3
SDS

RUO – Research Use Only

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