Hydroxyurea, 98%, Alfa Aesar™

Manufacturer: Alfa Aesar A1083114

Quantity 25g

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Catalog No. AAA1083114

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    Chemical Identifiers

    CAS 127-07-1
    Molecular Formula CH4N2O2
    Formula Weight 76.06g/mol
    MDL Number MFCD00007943
    Beilstein 1741548
    Merck Index 14,4848
    Chemical Name or Material Hydroxyurea

    Specifications

    Melting Point ≈140°C (dec.)
    Quantity 25g
    CAS 127-07-1
    Molecular Formula CH4N2O2
    Formula Weight 76.06g/mol
    MDL Number MFCD00007943
    Beilstein 1741548
    Merck Index 14,4848
    Health Hazard 1 Danger
    Health Hazard 2 GHS H Statement
    H340-H360;
    May cause genetic defects.
    May damage fertility or the unborn child.
    Health Hazard 3 GHS P Statement
    P281-P201-P202-P308+P313-P405-P501a;
    Use personal protective equipment as required.
    Obtain special instructions before use.
    Do not handle until all safety precautions have been read and understood.
    IF exposed or concerned: Get medical advice/attention.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    RTECS Number YT4900000
    Chemical Name or Material Hydroxyurea
    Assay 98%

    Description

    Applications
    Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

    Solubility
    Soluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.

    Notes
    Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

    GHS H Statement
    H340-H360;
    May cause genetic defects.
    May damage fertility or the unborn child.

    GHS P Statement
    P281-P201-P202-P308+P313-P405-P501a;
    Use personal protective equipment as required.
    Obtain special instructions before use.
    Do not handle until all safety precautions have been read and understood.
    IF exposed or concerned: Get medical advice/attention.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Danger

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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