Invitrogen™ ICT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588159

Catalog No. PIPA588159

Description

Immunogen sequence: LHKQKDGTEF KSIYSLDKLY PESQGSDTAW RVPNGAKQAD SDIPLDRLTI SYCRSSGPGG QNVNKVNSKA EVRFHLATAE WIAEPVRQKI AITHKNKINR LGELILTSES SRYQFRNLAD CLQKIRDMIT EASQTPKEPT KEDVKLHRIR IENMNRERLR QKRIHSAVKT SRRVDMD; Positive Samples: Raji, HT-29, 293T, B-cell, Skov3, Mouse lung, Mouse kidney, Mouse brain; Cellular Location: Mitochondrion.

Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Specifications

• Antigen: ICT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL58
• Gene Alias: 1110001A02Rik; 1110002E03Rik; 39S ribosomal protein L58, mitochondrial; Digestion substraction 1; DS1; DS-1; Ict1; immature colon carcinoma transcript 1; immature colon carcinoma transcript 1 protein; Immature colon carcinoma transcript 1 protein homolog; Mitochondrial large ribosomal subunit protein mL62; mitochondrial ribosomal protein L58; MRPL58; MRP-L58; Peptidyl-tRNA hydrolase ICT1, mitochondrial
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3396, 68572
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.23 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q14197, Q8R035
• Gene Symbols: MRPL58
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-206 of human ICT1 (NP_0015361).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov