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IDH1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 233091AP

Catalog No. 50-173-4045


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Description

Description

This antibody is specific to IDH1.

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described.
Specifications

Specifications

IDH1
0.47 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O75874, O88844, P41562
IDCD, IDH, IDH1, IDP, IDPC, NADP(+) specific ICDH, Oxalosuccinate decarboxylase, PICD
Rabbit
IgG
150 μL
-20°C
Primary
15926, 24479, 3417
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
IDH1
Liquid
IDH1
IDH1 Fusion Protein Ag19749
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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