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IDH3B Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550336

Catalog No. PA550336


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Description

Description

The antibody detects endogenous levels of total IDH3B protein.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predomitly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Specifications

Specifications

IDH3B
Polyclonal
Unconjugated
IDH3B
Liquid
IDH3B
Fusion protein corresponding to a region derived from internal residues of human isocitrate dehydrogenase 3 (NAD+) beta
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.4 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
O43837
RP46, H-IDHB
Rabbit
IgG
100 μL
-20°C
Primary
170718, 3420
Documents
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