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IEM 1925 dihydrobromide, Tocris Bioscience™

Catalog Number p-4817287
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
258282-23-4
C17H30Br2N2
422.249
ZCYUSVRXEKAQSL-UHFFFAOYSA-N
iem 1925 dihydrobromide, n-1-phenylcyclohexyl-1,5-pentanediamine dihydrobromide
44561101
N'-(1-phenylcyclohexyl)pentane-1,5-diamine;dihydrobromide
C1CCC(CC1)(C2=CC=CC=C2)NCCCCCN.Br.Br
This item is not returnable. View return policy
258282-23-4
C17H30Br2N2
422.249
ZCYUSVRXEKAQSL-UHFFFAOYSA-N
iem 1925 dihydrobromide, n-1-phenylcyclohexyl-1,5-pentanediamine dihydrobromide
44561101
N'-(1-phenylcyclohexyl)pentane-1,5-diamine;dihydrobromide
C1CCC(CC1)(C2=CC=CC=C2)NCCCCCN.Br.Br

Voltage- and use-dependent open-channel antagonist of AMPA receptors

IEM 1925 dihydrobromide is a voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking receptors more potently than GluA2-containing receptors (KD for GluA2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 (Cat. No. 1636) and IEM 1754 due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.
Quantity 10 mg
Formula Weight 422.24
Percent Purity 95%
Chemical Name or Material IEM 1925 dihydrobromide
Recommended Storage Desiccate at Room Temperature
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