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IEM 1925 dihydrobromide, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
IEM 1925 dihydrobromide is a voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking receptors more potently than GluA2-containing receptors (KD for GluA2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 (Cat. No. 1636) and IEM 1754 due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.
Specifications
Quantity | 10 mg |
Formula Weight | 422.24 |
Percent Purity | 95% |
Chemical Name or Material | IEM 1925 dihydrobromide |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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