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IFN alpha Mouse anti-Human, Clone: AB5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524776

Catalog No. PIMA524776


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Description

Description

Interferon Alpha (AB5).

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.
Specifications

Specifications

IFN alpha
Monoclonal
Unconjugated
IFNA1
Liquid
IFNA1
Recombit human interferon alpha-A.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
AB5
PBS with 0.09% sodium azide; pH 7.4
P01562
IFL, IFN, IFNA13, IFNAalphaIFN-alpha-1/13, IFN-ALPHA, IFN-alpha 1b, IFN-alphaD, interferon alpha 1b, interferon alpha-1/13, Interferon alpha-D, interferon, alpha 1, LeIF D, MGC138207, MGC138505, MGC138507
Mouse
IgG1
200 μg
4° C, do not freeze
Primary
3439
Documents
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