IFT57 Mouse anti-Human, Clone: OTI2G3, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA500917
DescriptionHIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5 ft.-AAAGACATG-3 ft. present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|ESRRBL1, HIPPI, MHS4R2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of human IFT57 produced in HEK293T cell.|
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