IgA (α-Heavy Chain) Ab-2 Rabbit Polyclonal Antibody, Epredia™

IgA (α-Heavy Chain) Ab-2, Rb PAb is one marker in a comprehensive ab portfolio that addresses all major disease states, ensuring the ideal tests are always available.

Supplier:  Epredia RB1433A

Catalog No. RB1433A

Description

The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: IgA isolated from a pool of normal human sera

Molecular Weight: 50kDa

Positive Control: Tonsil

Cellular Localization: Cytoplasmic Ab-2 recognizes a protein of 50kDa, identified as alpha heavy chain of human immunoglobulins. It reacts with both IgA1 and IgA2 isotypes. Ab-2 does not cross-react with γ (IgG), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Ab-2 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: IgA (alpha-Heavy Chain) Ab-2
• Classification: Polyclonal
• Host Species: Rabbit
• Quantity: 1 mL
• Research Discipline: Immunoglobulins
• Target Species: Human
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Immunogen: IgA isolated from a pool of normal human sera
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated