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IgE Rat anti-Mouse, Biotin, Clone: 23G3, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$95.00 - $196.00

Specifications

Antigen IgE
Clone 23G3
Target Species Mouse
Conjugate Biotin
Isotype IgG1, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-121-08 Non-distribution product as customer accommodation.
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Invitrogen
13599281
50 μg
Each for $95.00
Add to cart
 
50-121-09 Non-distribution product as customer accommodation.
View Documents
Invitrogen
13599282
100 μg
Each for $196.00
Add to cart
 
Description

Description

Description: The 23G3 monoclonal antibody reacts with the epsilon heavy chain of mouse IgE. It does not react with other classes of mouse immunoglobulin including IgD, IgG, IgA, or IgM. Applications Reported: The 23G3 antibody has been reported for use in flow cytometric analysis, and ELISA. Applications Tested: The 23G3 antibody has been tested by ELISA and can be used at 1:5000-1:10000. This 23G3 antibody has also been tested by flow cytometric analysis of IGEL cells, and can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 µm post-manufacturing filtered.

IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with 4 Ig-like constant domains, and two light chains. IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, anaphylatic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils that promote allergic manifestations. IgE is also functionally important for immunity against parasites.
Specifications

Specifications

IgE
Mouse
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, do not freeze
23G3
Biotin
ELISA, Flow Cytometry
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.

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