IGF1R Mouse anti-Human, Clone: JBW902, Abnova™
Mouse monoclonal antibody raised against human IGF1R
Manufacturer: Abnova Corporation MAB12559
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq]
|Mouse monoclonal antibody raised against human IGF1R|
|In 0.1M Tris-glycine, 0.15M NaCl, pH 7.4 (0.05% sodium azide).|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.|
|Recombinant GST fusion protein corresponding to amino acids 1264-1367 of human IGF1R.|
|Protein A purification|
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