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IGF2BP2 Mouse anti-Canine, Human, Non-human primate, Clone: OTI3G7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525130

Catalog No. PIMA525130


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Description

Description

IGF2BP2 (insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type 2 diabetes mellitus.
Specifications

Specifications

IGF2BP2
Monoclonal
0.52 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9Y6M1
IMP-2, IMP2, VICKZ2, p62, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, VICKZ family member 2, hepatocellular carcinoma autoantigen p62, insulin-like growth factor 2 mRNA-binding protein 2
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10644, 478662, 700598
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3G7
Unconjugated
IGF2BP2
Liquid
IGF2BP2
Full length human recombit protein of IGF2BP2 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Non-human primate
Documents
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