IGF2BP3 Mouse anti-Human, Clone: OTI6A3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527484
DescriptionInsulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some maligcies. IMP-3 is expressed in maligt melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of maligt melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|CT98, IMP-3, IMP3, KOC1, VICKZ3, IGF II mRNA binding protein 3, IGF-II mRNA-binding protein 3, IGF2 mRNA-binding protein 3, KH domain containing protein overexpressed in cancer, KH domain-containing protein overexpressed in cancer, VICKZ family member 3, cancer/testis antigen 98, hKOC, insulin-l|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of IGF2BP3 produced in E.coli|
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