IgG/IgM, Polyclonal, Secondary Antibody, BD
Manufacturer: BD Biosciences 555988
Monoclonal antibody BB9 recognizes a cell-surface glycoprotein of approximately 160kDa, expressed on primitive hematopoietic progenitor cells (HPC). This antibody was generated using human bone marrow-derived stromal cells as immunogen. BB9 reacts with stromal cells, a minor subset of human bone marrow cells; it does not react with peripheral blood leukocytes. Reacts with a subset of CD34+, CD90+ demonstrating low or absent expression of CD38, low retention of Rhodamine 123 and Ki-67-. CD34+BB9+ cells are able to sustain hematopoiesis in pre-CFU culture stimulated with IL-3, IL-6, G-CSF and SCF. BB9 also reacts with a subset of CD34+ cells from mobilized peripheral blood.
Host Species: Mouse
Isotype: IgG1, κ
Species Reactivity: Goat
Immunogen: Human bone marrow-derived stromal cells
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