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Lambda light chain Mouse anti-Human, Clone: HP6054, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524718

Catalog No. PIMA524718


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Description

Description

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)
Specifications

Specifications

Lambda light chain
Monoclonal
1 mg/mL
PBS with 0.09% sodium azide
P0CG04
Ig lambda chain V-I region NEW, LV103
Mouse
IgG2a, kappa
400 μL
-20°C
Primary
3537
Immunohistochemistry (Paraffin), Western Blot
HP6054
Unconjugated
IGLC1
Liquid
IGLC1
human Lambda light chain recombit protein
Protein G
RUO
Antibody
Monoclonal
Human
Documents
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