Learn More
IgM Monoclonal Antibody (II/41), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
$148.00 - $195.65
Specifications
Antigen | IgM |
---|---|
Clone | II/41 |
Concentration | 0.5 mg/mL |
Applications | Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin) |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
13-579-082
|
Invitrogen
13579082 |
100 μg |
Each for $148.00
|
|
|||||
50-119-22
|
Invitrogen
13579085 |
500 μg |
Each
for $195.65
Save 4% Reg : |
|
|||||
Description
Description: The II/41 monoclonal antibody reacts with the μ heavy chain of mouse IgM. It does not react with other classes of mouse immunoglobulin including IgD, IgG or IgA. IgM is expressed intracellularly, during early stages of B lymphopoiesis, and then on the surface of more mature B cells in the bone marrow and peripheral B cells. Fluorochrome conjugated II/41 can be used as a detection secondary for mouse IgM. Applications Reported: The II/41 antibody has been reported for use in flow cytometric analysis, immunohistochemistry, and immunocytochemistry. Applications Tested: The II/41 antibody has been tested by flow cytometric analysis of mouse spleen cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.
Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen. It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum. Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens. It plays a crucial role in the innate immune response and is important for neutralizing pathogens before the adaptive immune response is fully activated. Mouse IgM is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.Specifications
IgM | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH | |
Ighm | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
II/41 | |
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin) | |
Biotin | |
Rat | |
Mouse | |
P01872 | |
16019 | |
IgG2a κ | |
Affinity chromatography | |
Ighm |
For Research Use Only.
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.