IKK alpha Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA595190

Catalog No. PIPA595190

Description

Human IKK alpha shares 98% amino acid (aa) sequence identity with mouse IKK alpha. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL.

CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.

Specifications

• Antigen: IKK alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHUK
• Gene Alias: AI256658, CHUK, Chuk1, component of inhibitor of nuclear factor kappa B kinase complex, conserved helix-loop-helix ubiquitous kinase, EC 2.7.11.10, Fbx24, Fbxo24, FLJ40509, I kappa B kinase 1, i kappa-B kinase alpha, ikappaB kinase, I-kappa-B kinase 1, I-kappa-B kinase 2, IkappaB kinase alpha, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, IkB kinase alpha subunit, IkB kinase-alpha, ikBKA, IKBKB, IKK alpha, IKK1, IKK2, Ikka, IKK-A, IKK-a kinase, IKK-alpha, IKKB, IKK-B, IKK-beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, kinase beta, MGC131801, NFKBIKA, NFKBIKB, Nuclear factor NFkappaB inhibitor kinase alpha, Nuclear factor NF-kappa-B inhibitor kinase alpha, TCF16, TCF-16, Transcription factor 16
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1147, 12675
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5MG BSA and 0.05MG sodium azide
• Gene Accession No.: O15111, Q60680
• Gene Symbols: CHUK
• Immunogen: E.coli-derived human IKK alpha recombinant protein (Position: V411-E745).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG