IKZF3 Mouse anti-Human, Clone: OTI1E1, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF804235
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOIKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
|Human recombit protein fragment corresponding to amino acids 1-301 of human IKZF3 produced in E.coli.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|AIO, AIOLOS, ZNFN1A3|
|-20° C, Avoid Freeze/Thaw Cycles|
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