Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

IL-17AF Rat anti-Mouse, PE, Clone: B8KN8R, eBioscience™ Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Catalog No. 12-917-182


Add to cart

Description

Description

The B8KN8R MAb reacts with mouse interleukin (IL)-17AF heterodimer. This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers. IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.

IL-17AF Monoclonal antibody specifically detects IL-17AF in Mouse samples. It is validated for Flow Cytometry
Specifications

Specifications

Liquid
Flow Cytometry
B8KN8R
PE
Il17a
C87042; CANDF6; Ctla8; Ctla-8; cytokine ML-1; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; IL17; IL-17; Il17a; IL-17A; IL17F; IL-17F; ILN; Interleukin; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17F; Interleukin-17A; Interleukin-17F; ML1; ML-1
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16171, 257630
IL-17AF
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q62386, Q7TNI7
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
SDS
Documents
Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit