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IL-2 Rabbit anti-Human, Biotin, Polyclonal, eBioscience™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen 13702885

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Catalog No. 50-112-2569


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Description

Description

Description: The rabbit anti-human IL-2 polyclonal antibody reacts with human interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. Applications Reported: This polyclonal antibody has been reported for use in detection of human IL-2 by ELISA. Applications Tested: The biotinylated polyclonal rabbit anti-human IL-2 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human IL-2 in combination with the purified MQ1-17H12 (14-7029) antibody for capture and recombit human IL-2 (14-8029) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 µg/mL. A standard curve consisting of doubling dilutions of the recombit standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. Filtration: 0.2 µm post-manufacturing filtered.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Specifications

Specifications

IL-2
Polyclonal
Biotin
IL2
Liquid
IL2
IgG
500 μg
4° C, do not freeze
Primary
3558
ELISA
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P60568
Interleukin-2, T-cell growth factor, TCGF, Aldesleukin
Rabbit
Affinity chromatography
RUO
Antibody
Polyclonal
Human
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