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IL24 Mouse anti-Human, Clone: OTI3C5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527140

Catalog No. PIMA527140


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Description

Description

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in maligt gliomas in a p53-independent manner.
Specifications

Specifications

IL24
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q13007
C49A;FISP;IL 24;IL 4 induced secreted protein;IL-24;IL10B;Il24;IL24_HUMAN;interleukin 24;Interleukin-24;MDA-7;MDA7;Melanocyte associated Mda 7;Melanoma differentiation association protein 7;Melanoma differentiation-associated gene 7 protein;Mob5;ST16;Suppression of tumorigenicity 16 (melanoma differentiation);Suppression of tumorigenicity 16;Suppression of tumorigenicity 16 protein;
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
11009
Immunohistochemistry (Paraffin), Western Blot
OTI3C5
Unconjugated
IL24
Liquid
IL24
Human recombit protein fragment corresponding to amino acids 52-206 of IL24 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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