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IL-5 Rat anti-Human, Biotin, Clone: JES1-5A10, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$118.00 - $290.00

Specifications

Antigen IL-5
Clone JES1-5A10
Target Species Human
Conjugate Biotin
Isotype IgG2a, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-121-61 Non-distribution product as customer accommodation.
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Invitrogen
13705981
50 μg Each for $118.00
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50-121-62 Non-distribution product as customer accommodation.
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Invitrogen
13705985
500 μg Each for $290.00
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Description

Description

Description: The JES1-5A10 antibody reacts with human interleukin-5 (IL-5), also known as BCDF-alpha and eosinophil differentiation factor (EDF). This 15-20 kDa cytokine is secreted by T cells and exists a homodimer. Applications Reported: JES1-5A10 has been reported for use in detection of human IL-5 by ELISA. Applications Tested: The JES1-5A10 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human Interleukin-5 (IL-5) in combination with the purified TRFK5 (14-7052) antibody for capture and recombit human IL-5 (14-8059) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 µg/mL. A standard curve consisting of doubling dilutions of the recombit standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate. Filtration: 0.2 µm post-manufacturing filtered.

IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Specifications

Specifications

IL-5
Human
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
JES1-5A10
Biotin
ELISA
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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