Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

IL12B Mouse anti-Human, Clone: C8.6, Abnova™

Mouse monoclonal antibody raised against human IL12B.

Manufacturer:  Abnova Corporation MAB12705

Catalog No. 89-934-359


Add to cart

Description

Description

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq]

Specifications

Specifications

IL12B
C8.6
Mouse monoclonal antibody raised against human IL12B.
In PBS, 150mM NaCl, pH 7.2 (0.09% sodium azide).
CLMF/CLMF2/IL-12B/NKSF/NKSF2
Mouse
IgG1, kappa
50 ug
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20-40 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Liquid
IL12B
Huamn IL12B
Affinity purification
RUO
Primary
3593
SDS
Documents
Product Certifications
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit