Invitrogen™ IL15RA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579467

Catalog No. PIPA579467

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue. IHC: mouse brain tissue, rat brain tissue. ICC/IF: K562 cell. Flow: K562 cell.

Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.

Specifications

• Antigen: IL15RA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL15RA
• Gene Alias: AA690181; CD215; IL 15 receptor; IL 15 receptor subunit a; IL 15R; IL 15R alpha; IL 15R a; IL15 receptor; IL15 receptor subunit alpha; IL-15 receptor subunit alpha; IL15 receptor subunit a; IL15R; IL15R alpha; IL15R a; Il15ra; IL-15RA; IL-15R-alpha; Interleukin 15 receptor; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; interleukin 15 receptor subunit alpha; Interleukin 15 receptor subunit a; interleukin 15 receptor, alpha; interleukin 15 receptor, alpha chain; interleukin-15 receptor subunit alpha; sIL 15R; sIL-15 receptor subunit alpha; sIL15R; sIL-15RA; sIL-15R-alpha; soluble IL 15R; soluble IL15R; Soluble interleukin-15 receptor subunit alpha
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16169, 3601, 690369
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4 mg trehalose and 0.05 mg sodium azide
• Gene Accession No.: Q13261, Q60819
• Gene Symbols: IL15RA
• Immunogen: E. coli-derived human IL15RA recombinant protein (Position: I31-T174).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov