Invitrogen™ IL18R1 Monoclonal Antibody (70625.111)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA124813

Catalog No. PIMA124813

Description

In Neutralization assays at a concentration of 0.12 μg/mL, this antibody will neutralize 50% of the bioactivity due to 50 ng/mL recombinant human IL18 using activated human T cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.

Specifications

• Antigen: IL18R1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q13478
• Gene Symbols: Il18r1
• Immunogen: Recombinant, full length human IL18R1 protein expressed in mouse NSO cells.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 70625.111
• Conjugate: Unconjugated
• Gene: Il18r1
• Gene Alias: CD218 antigen-like family member A; CD218a; CDw218a; cytokine receptor; IL1 receptor-related protein; Il18r1; IL-18R1; IL-18R-1; IL18RA; Il18ralpha; IL-18R-alpha; IL18Ralpha2; IL1RRP; IL-1Rrp; IL1R-rp; interleukin 1 receptor related protein; interleukin 18 receptor 1; Interleukin-18; interleukin-18 receptor 1; Interleukin-18 receptor alpha
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 8809
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid