IL1RAPL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 216091AP
DescriptionThe protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P59823, P59824, Q9NZN1|
|IL 1 RAPL 1, IL 1RAPL 1, IL1R8, IL1RAPL, IL1RAPL 1, IL1RAPL1, MRX10, MRX21, MRX34, Oligophrenin 4, OPHN4, TIGIRR 2|
|11141, 317553, 331461|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation|
|IL1RAPL1 Fusion Protein Ag16252|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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