IL24 Mouse anti-Human, Clone: OTI4H4, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF809452
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOInterleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in maligt gliomas in a p53-independent manner.
|Human recombit protein fragment corresponding to amino acids 52-206 of human IL24 produced in E.coli.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|C49A, FISP, IL10B, MDA7, MOB5, ST16|
|-20° C, Avoid Freeze/Thaw Cycles|
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