ILT5/CD85a/LILRB3 Mouse anti-Human, Clone: 4F9, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10064329

Catalog No. NB10064329

Description

ILT5/CD85a/LILRB3 Monoclonal specifically detects ILT5/CD85a/LILRB3 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.

Specifications

• Antigen: ILT5/CD85a/LILRB3
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:100
• Gene Alias: CD85 antigen-like family member A, CD85a antigen, HL9Immunoglobulin-like transcript 5, ILT-5, ILT5CD85a, Leukocyte immunoglobulin-like receptor 3, leukocyte immunoglobulin-like receptor subfamily B member 3, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR3CD85A, LIR-3MGC138403, member 3, Monocyte inhibitory receptor HL9, PIRB
• Host Species: Mouse
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 11025
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
• Clone: 4F9
• Conjugate: Unconjugated
• Gene Accession No.: Q8NHL6
• Gene Symbols: LILRB3
• Immunogen: Monocyte derived dendritic cells
• Quantity: 0.1 mg
• Primary or Secondary: Primary
• Test Specificity: NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1

For Research Use Only