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Importin beta Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 100771AP150UL

Encompass_Preferred

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Catalog No. 50-172-6004


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Description

Description

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
Specifications

Specifications

Importin beta
Polyclonal
Unconjugated
KPNB1
IMB1, Impnb, Importin 90, Importin subunit beta 1, IPO1, IPOB, karyopherin (importin) beta 1, Karyopherin subunit beta 1, KPNB1, NTF97, Nuclear factor p97, PTAC97
Rabbit
Antigen Affinity Chromatography
RUO
16211, 24917, 3837
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot
0.15 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P52296, P70168, Q14974
Kpnb1
Importin beta Fusion Protein Ag0122
150 μL
Primary
Human, Mouse, Rat
Liquid
Safety and Handling

Safety and Handling

SDS
Documents
Product Certifications
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