Inhibitor of calcineurin-substrate association
Manufacturer: Tocris 2162/10
DescriptionInhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (Kd = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT.
- Chemical Name: 9,10-Dihydro-9,10[1',2']-benzenoanthracene-1,4-dione
- Formula: C20H12O2
- CAS Number: 3519-82-2
- Solubility: Soluble to 20mM in DMSO
- Purity: >98
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok