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Alfa Aesar™ Indole-3-carbonitrile, 98%

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Quantity:
1g
5g
25g
5457-28-3
C9H6N2
142.161
MFCD00022717
CHIFTAQVXHNVRW-UHFFFAOYSA-N
3-cyanoindole,indole-3-carbonitrile,3-indolecarbonitrile,chembl46724,zlchem 360,3-cyano-1h-indole,pubchem7325,acmc-209lhi,1h-indol-3-yl cyanide
230282
1H-indole-3-carbonitrile
C1=CC=C2C(=C1)C(=CN2)C#N
5457-28-3
C9H6N2
142.161
MFCD00022717
CHIFTAQVXHNVRW-UHFFFAOYSA-N
3-cyanoindole,indole-3-carbonitrile,3-indolecarbonitrile,chembl46724,zlchem 360,3-cyano-1h-indole,pubchem7325,acmc-209lhi,1h-indol-3-yl cyanide
230282
1H-indole-3-carbonitrile
C1=CC=C2C(=C1)C(=CN2)C#N
Applications
Indole-3-carbonitrile is used as a synthesis reagent for preparation of 4-substituted β-lactams, biologically active indoles, inhibitors of glycogen synthase kinase 3β (GSK-3), indole fragments as inosine monophosphate dehydrogenase (IMPDH) inhibitors and HIV-1 integrase inhibitors. It is also used as a reactant for intramolecular oxidative C-H coupling reactions with applications in medium-ring synthesis techniques and for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators.

Solubility
Insoluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to light.
Sensitivity Light sensitive
Quantity 25g
Melting Point 177°C to 182°C
Odor Odorless
Beilstein 120888
Solubility Information Insoluble in water.
Formula Weight 142.16
Percent Purity 98%
Chemical Name or Material Indole-3-carbonitrile

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

H302+H312+H332-H315-H319-H335

DOTInformation : Hazard Class: 6.1; Packaging Group: III

EINECSNumber : 000-000-0

TSCA : No

Recommended Storage : Ambient temperatures