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Tocris Bioscience™ INDY

Name: Tocris Bioscience&trade; INDY
Brand: Tocris Bioscience&trade;
SKU: 49-971-0R
Price: 261.00 USD

DYRK1A/B inhibitor

Supplier: Tocris Bioscience™ 4997/10

Catalog No. 49-971-0R

$261.00 / Each of 1

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Description

INDY is a DYRK1A/B inhibitor (IC50 values are 0.23 and 0.24 μM, for DYRK1B and DYRKA respectively). Binds at the ATP-binding cleft of the enzyme. Reverses aberrant tau-phosphorylation and rescues repressed calcineurin/NFAT signaling. Impairs the self-renewal capacity of subventricular zone neural stem cells. Also available as a prodrug, proINDY (Cat. No. 4998).

Specifications

Purity	>98%
Product Type	INDY
Inhibitors	INDY

Quantity	10 mg
Molecular Weight (g/mol)	235.3

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Tocris Bioscience™ INDY

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