Invitrogen™ ING5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596627

Catalog No. PIPA596627

Description

Immunogen sequence: MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSPDQ RVERLQKIQN AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKMEGSDF ESSGGRGLKK GRGQKEKRGS RGRGRRTSEE DTPKKKKHKG GSEFTDTILS VHPSDVLDMP VDPNEPTYCL CHQVSYGEMI GCDNPDCPIE WFHFACVDLT; Positive Samples: Jurkat, A-549, 293T; Cellular Location: Nucleus.

ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.

Specifications

• Antigen: ING5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ING5
• Gene Alias: 1700001C14Rik; 1700027H23Rik; 1810018M11Rik; AI225768; ING5; inhibitor of growth family member 5; inhibitor of growth family, member 5; inhibitor of growth protein 5; p28ING5
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84289
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8WYH8
• Gene Symbols: ING5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ING5 (NP_1157052).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG