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INHBB Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550818

Catalog No. PA550818


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Description

Description

The antibody detects endogenous levels of total INHBB protein.

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
Specifications

Specifications

INHBB
Polyclonal
Unconjugated
INHBB
Liquid
INHBB
Synthetic peptide of human inhibin, beta B
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin)
2.9 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
P09529, Q04999, P17491
Inhibin beta B chain
Rabbit
IgG
100 μL
-20°C
Primary
16324, 25196, 3625
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