INHBB Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550818
The antibody detects endogenous levels of total INHBB protein.The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
|Synthetic peptide of human inhibin, beta B|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 40% glycerol and 0.05% sodium azide; pH 7.4|
|P09529, Q04999, P17491|
|Inhibin beta B chain|
|16324, 25196, 3625|
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