INO80 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 188101AP
DescriptionDNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|hINO80, INO80, INO80 homolog (S. cerevisiae), INO80A, INOC1, KIAA1259|
|296084, 54617, 68142|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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