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INPP5D Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 196941AP

Catalog No. 50-173-2491


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Description

Description

This antibody is specific to INPP5D.

an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1, 3, 4, 5)P4 and PtdIns(3, 4, 5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus. Upon receptor cross-linking, SHIP is first recruited to the plasma membrane by its SH2, followed by tyrosine phosphorylation on the NPXY motif. Both membrane relocalization and phosphorylation are essential for its regulatory function. Associates with SHC after cytokine stimulation.
Specifications

Specifications

INPP5D
0.26 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P97573, Q92835, Q9ES52
hp51CN, INPP5D, p150Ship, SHIP, SHIP 1, SHIP1, SIP 145
Rabbit
IgG
150 μL
-20°C
Primary
16331, 3635, 54259
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
INPP5D
Liquid
INPP5D
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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