INS Mouse anti-Human, Clone: INS04 + INS05, Abnova™
Mouse monoclonal antibody raised against human INS.
Manufacturer: Abnova Corporation MAB12631
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]
|INS04 + INS05|
|Mouse monoclonal antibody raised against human INS.|
|In 10mM PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).|
|Protein G purification|
|Immunohistochemistry (PFA fixed)|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.|
|Store at 4°C. Do not freeze.|
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