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INSRR Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549383

Catalog No. PA549383


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Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Specifications

Specifications

Insrr
Polyclonal
Unconjugated
Insrr
Liquid
INSRR
KLH conjugated synthetic peptide between 1265-1295 amino acids from the C-terminal region of Mouse Insrr.
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Rat
Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q64716
Insulin receptor-related protein, IRR, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, Insrr, Irr
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
60663
Documents
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