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Thermo Scientific™ Lab Vision™ Insulin Receptor (α -Subunit) Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ Insulin Receptor (α-Subunit) Ab-1, Mouse Monoclonal Antibody.

$171.10 - $1004.00

Specifications

Antigen Insulin Receptor (alpha-Subunit) Ab-1
Clone 83-14
Applications Immunoprecipitation
Classification Monoclonal
Format Concentrated
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Products 8
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS631B
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Thermo Scientific™
MS631B
200μg/mL Biotin 1mL Each for $1,004.00
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MS631B0
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Thermo Scientific™
MS631B0
200μg/mL Biotin 100μL Each for $231.00
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MS631B1
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Thermo Scientific™
MS631B1
200μg/mL Biotin 500μL Each for $672.00
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MS631P
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Thermo Scientific™
MS631P
200μg/mL Unconjugated 1mL Each for $806.50
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MS631P0
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Thermo Scientific™
MS631P0
200μg/mL Unconjugated 100μL Each for $171.10
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MS631P1
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Thermo Scientific™
MS631P1
200μg/mL Unconjugated 500μL Each for $501.50
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MS631P1ABX
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Thermo Scientific™
MS631P1ABX
1mg/mL Unconjugated 100μL Each for $557.50
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MS631PABX
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Thermo Scientific™
MS631PABX
1mg/mL Unconjugated 200μL Each for $885.50
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Description

Description

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ Insulin Receptor (α-Subunit) Ab-1, Mouse Monoclonal Antibody.

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: 83-14

Isotype: IgG2a/κ

Species Reactivity: Human. Weakly with Cow, Pig and Sheep. Does not react with rabbit, mouse and rat. Others not known.

Epitope: aa 469-592 (exon 7/8)

Immunogen: IM-9 lymphocytes followed by purified insulin receptor

Molecular Weight: 135kDa

Positive Control: IM-9 lymphocyte cells, Placenta

Cellular Localization: Membrane Ab-1 inhibits insulin binding and mimics insulin action. It is excellent for immunoprecipitation of alpha-subunit of IR.

Recommended for:

  • Immunoprecipitation
  • ELISA
  • Insulin-like Agonist
  • Inhibits (~80%) Insulin Binding (10nM)
  • Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Insulin Receptor (alpha-Subunit) Ab-1
Immunoprecipitation
Concentrated
RUO
Primary
IgG2a kappa
83-14
Monoclonal
Murine
Steroids Hormones and Growth Factors
IM-9 lymphocytes followed by purified insulin receptor
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