Integrin alpha 2b/CD41 Mouse anti-Human, Mustelid, Baboon, Clone: PM6/248, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NB10063779	Novus Biologicals NB10063779	0.1 mg
NB017555	Novus Biologicals NB100637790.025MG	0.025 mg

Description

Integrin alpha 2b/CD41 Monoclonal specifically detects Integrin alpha 2b/CD41 in Human, Mustelid, Baboon samples. It is validated for Flow Cytometry.

Specifications

• Antigen: Integrin alpha 2b/CD41
• Concentration: 1.0 mg/mL
• Applications: Flow Cytometry
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Mustelid, Baboon
• Gene Accession No.: P08514
• Gene ID (Entrez): 3674
• Immunogen: Human platelet plasma membrane
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

• Clone: PM6/248
• Dilution: Flow Cytometry 1:10-1:1000
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Formulation: Phosphate buffered saline with 0.09% Sodium Azide
• Gene Alias: CD41, CD41 antigen, CD41BHPA3, GP2Bintegrin alpha-IIb, GPalpha IIb, GPIIb, GTA, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41), integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B), ITGAB, platelet fibrinogen receptor, alpha subunit, Platelet membrane glycoprotein IIb, platelet-specific antigen BAK
• Gene Symbols: ITGA2B
• Isotype: IgG1
• Purification Method: Protein G purified
• Test Specificity: NB100-63779 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.

For Research Use Only