Integrin alpha 4/CD49d Mouse anti-Human, Clone: 44H6, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NB10064903	Novus Biologicals NB10064903	0.1 mg
NB017661	Novus Biologicals NB100649030.025MG	0.025 mg

Description

Integrin alpha 4/CD49d Monoclonal specifically detects Integrin alpha 4/CD49d in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin (Negative).

Specifications

• Antigen: Integrin alpha 4/CD49d
• Concentration: 1.0 mg/mL
• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cancer, Cellular Markers, Cytoskeleton Markers
• Gene Accession No.: P13612
• Gene ID (Entrez): 3676
• Immunogen: HOON pre-B leukemia cell line
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

• Clone: 44H6
• Dilution: Flow Cytometry 1:40, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:50-1:100, Immunohistochemistry-Paraffin (Negative)
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Alias: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
• Gene Symbols: ITGA4
• Isotype: IgG1
• Purification Method: Protein A or G purified
• Test Specificity: NB100-64903 recognizes CD49d, also known as Integrin alpha 4, which associates with either CD29 (integrin beta 1) or integrin beta 7. CD49d is a 150kD molecule, which may be cleaved to 80kD and 70kD fragments. It is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin. 44H6 induces homotypic aggregation.

For Research Use Only