Integrin beta 4/CD104 Mouse anti-Human, Alexa Fluor 532, Clone: UM-A9, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234507AF532
DescriptionIntegrin beta 4/CD104 Monoclonal antibody specifically detects Integrin beta 4/CD104 in Human samples. It is validated for Western Blot,Flow Cytometry,ELISA,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen).
|Integrin beta 4/CD104|
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen|
|CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4|
|Store at 4°C in the dark.|
|Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot|
|Alexa Fluor™ 532|
|50 mM sodium borate with 0.05% sodium azide|
|Human squamous cell carcinoma (UM-SCC1)|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok