Integrin beta-4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 252771AP
DescriptionProtein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|A2A863, P16144, Q64632|
|CD104, GP150, Integrin beta 4, integrin, beta 4, ITGB4|
|192897, 25724, 3691|
|Immunohistochemistry (Paraffin), Western Blot|
|Integrin beta-4 Fusion Protein Ag16460|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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